fresh or frozen egg donation

Choosing between fresh or frozen egg donation

November 8, 2017

When deciding whether to use fresh or frozen egg donation, talk with your agency. They will take into consideration your requirements and then match you with available eggs and egg donors to find the perfect match for you.

Whether you choose frozen eggs or fresh eggs, egg donation can help you build your family when your eggs aren’t up for the job. 

After several cycles of IVF using your own eggs with no success, your fertility center has normally determined that the problem is with the quality of your eggs. Your eggs just aren’t creating viable embryos or embryos that implant properly. There are many reasons your eggs aren’t working out, these include:

  • premature ovarian failure (menopause before age 40)
  • diminished ovarian reserve
  • lower quantity of eggs due to the woman’s age
  • previous failed IVF cycles, which may be due to poor egg quality
  • being a carrier for genetic abnormalities which can be inherited
Whatever the reason for the failure, the writing on the wall says: “donor egg.” Egg donation is in your future so now you have to decide between fresh and frozen eggs. There is no automatic right answer for everybody but here are some of the factors to consider when making this momentous decision.


Will donor eggs help me get pregnant?

The answer in almost all cases is yes! The primary reason a lot of IVF cycles fail, when the woman is trying to use her own eggs, is because her eggs are simply too old. As women age their egg quality diminishes, even if they are still ovulating regularly. As you can see from the above list, the majority of the reasons eggs don’t fertilize or implant is due to the age of the egg. Studies have shown that older women who use younger eggs have the same chance of getting pregnant as a younger woman would. It really is “all about the eggs.”

Where can I find egg donors?

Your fertility center will have information on egg donation agencies and, depending on the type of eggs you’re looking for, can guide you to the one that suits your needs. Many fertility centers also have in-house egg donation agencies, if your center has one this would be the place to look first because the coordination will be easier as they will have a process in place already. Now the question is, do you want fresh or frozen eggs?

Are fresh or frozen eggs more successful? 

Studies have shown that the chances of a live birth resulting from a fresh egg donation IVF cycle was 9%-20% higher than from a frozen egg donation cycle. There are a lot of variable that go into that number, primarily the number of eggs available for use and possible damage to the eggs from freezing. During a fresh egg donation cycle the intended parents get all the eggs retrieved, this can be between 15 and 20 and is hardly ever below 10. While not all eggs will fertilize properly, if you start with 15 eggs you normally have 3-4 viable embryos to choose from and possibly some to freeze for later cycles.

Frozen eggs, on the other hand, come in batches of five to eight. While frozen eggs can be fertilized at almost the same rate as fresh, there still aren’t going to be as many embryos since you’re starting out with fewer eggs unless the donor is extremely fertile. This is a significant factor when making a decision, especially when you think about the physical, emotional and financial costs of repeated IVF cycles. By the time they get to the realization that they need donor eggs, most people have gone through several IVF cycles already and don’t want to go through an indefinite number of cycles.  Search carefully to find out the success rates in the clinics you are considering.

What’s so great about fresh eggs?

When you do an IVF cycle with fresh donated eggs the donor and recipient have to be in the same place at roughly the same time. If the donor has to travel then that has to be arranged ahead of time. The two women also have to have their cycles synced so the intended mother’s body is ready for the embryo transfer. This means both women have to be on fertility medication. All the timing issues can add to the amount of time between the decision to use donor eggs and the embryo transfer. Fresh donor eggs have been used for many years and are proven to work extremely well. Fertility clinics have to track and report their success rates, you can read about a clinic’s success rates with donor eggs on the SART (Society for Assisted Reproductive Technology) website or the CDC website. Of course a fresh egg cycle, especially if the recipients are keeping all the eggs, is the most expensive egg donation cycle., often 2-3 times more expensive than a frozen egg cycle.

What do frozen eggs have to offer?

One of the first things frozen eggs offer is convenience, they are already harvested so can be there when you need them. Since there is no synchronizing of cycles, frozen eggs can be used with the intended mother’s natural cycle. One of the major advantages of frozen eggs is the ability to get eggs from all different kinds of women without paying for them to travel to the intended parent’s fertility center. This is really a consideration because often the ideal egg donor for you might not be able to travel to your fertility center. Eggs are harvested and stored near the home of the donor and shipped to recipients, making timing a lot easier for everyone concerned.

They are also cheaper, this is because they are sold in units of five to eight so it’s possible for the egg donation agencies to get two batches from one donation. The donors are paid higher fees and these fees are often very high for a frozen cycle. Freezing eggs is now done using the vitrification process so there are no ice crystals forming within the egg that would damage it. Frozen eggs offer intended parents the widest range of possible donors at a reasonable price and the ability to work around their cycle or schedule. Frozen eggs are a wonderful alternative for people who need a certain type of donor or can’t afford the whole fresh egg donation process.

The best place to start, when deciding whether to use fresh or frozen eggs, is to talk with your egg donation agency. They will take into consideration your requirements and match them with the available eggs and egg donors. Whether you use fresh or frozen eggs, the young age and viability of the eggs can almost assure you a couple of healthy embryos ready to be implanted.

Author Bio:

Sophie Yang is a content writer at the Reproductive Services Medical Center, a full-service fertility clinic in San Diego features a full line-up of fertility services; including hassle-free egg donation process, sperm cryopreservation, IVF & IUI Fertility treatment and much more. She loves writing about the reproductive system and treatments for infertility. When she is not writing or working, you can find her gardening.










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